全部产品分类
品牌 |
Leading Biology | 货号 |
APR07073G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATP11C antibody (Center).
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分子量 |
129477 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A. Some cell membrane localization observed in the presence of TMEM30B
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宿主 |
Rabbit
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种属反应性 |
Human, Hamster, Mouse
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免疫原 |
589-616 aa
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靶点 |
This ATP11C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human ATP11C.
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亚型 |
Rabbit Ig
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通用名 |
ATPIG, ATPIQ
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基因ID |
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UniProt ID |
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功能 |
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Required for B cell differentiation past the pro-B cell stage. Seems to mediate phosphatidylserine (PS) flipping in pro-B cells. May be involved in the transport of cholestatic bile acids (By similarity).
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总结 |
The function of ATP11C remains unknown.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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别名 |
Phospholipid-transporting ATPase IG, ATPase IQ, ATPase class VI type 11C, P4-ATPase flippase complex alpha subunit ATP11C, ATP11C, ATPIG, ATPIQ
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图像 |
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说明书 |
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数量 |
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