全部产品分类
品牌 |
Leading Biology | 货号 |
APR12727G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PAX2 antibody (Center).
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分子量 |
44706 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
187-216 aa
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靶点 |
This PAX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human PAX2.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
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总结 |
PAX2 encodes paired box gene 2, one of many humanhomologues of the Drosophila melanogaster gene prd. The centralfeature of this transcription factor gene family is the conservedDNA-binding paired box domain. PAX2 is believed to be a target oftranscriptional supression by the tumor supressor gene WT1.Mutations within PAX2 have been shown to result in optic nervecolobomas and renal hypoplasia. Alternative splicing of this generesults in multiple transcript variants.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Paired box protein Pax-2, PAX2
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图像 |
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说明书 |
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数量 |
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