全部产品分类
品牌 |
Leading Biology | 货号 |
APR15336G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD1D antibody (Center).
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分子量 |
37717 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
177-206 aa
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靶点 |
This CD1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human CD1D.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
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总结 |
This gene encodes a divergent member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene localizes to late endosomes and lysosomes via atyrosine-based motif in the cytoplasmic tail.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Antigen-presenting glycoprotein CD1d, R3G1, CD1d, CD1D
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图像 |
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说明书 |
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数量 |
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