全部产品分类
品牌 |
Leading Biology | 货号 |
APR14400G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEC23IP antibody (C-term).
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分子量 |
111076 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Endoplasmic reticulum
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
724-752 aa
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靶点 |
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
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总结 |
COPII-coated vesicles are involved in protein transportfrom the endoplasmic reticulum to the Golgi apparatus. The proteinencoded by this gene was identified by its interaction with a mouseprotein similar to yeast Sec23p, an essential component of theCOPII. This protein shares significant similarity withphospholipid-modifying proteins, especially phosphatidic acidpreferring-phospholipase A1. Overexpression of this protein hasbeen shown to cause disorganization of the endoplasmicreticulum-Golgi intermediate compartment and Golgi apparatus, whichsuggests its role in the early secretory pathway. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
SEC23-interacting protein, p125, SEC23IP
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图像 |
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说明书 |
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数量 |
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