全部产品分类
品牌 |
Leading Biology | 货号 |
APR10581G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TSP1 antibody.
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分子量 |
129383 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum. Sarcoplasmic reticulum
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宿主 |
Rabbit
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种属反应性 |
Human, Rat
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靶点 |
TSP1
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亚型 |
Rabbit IgG
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通用名 |
TSP, TSP1
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基因ID |
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UniProt ID |
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功能 |
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
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总结 |
Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. It has also been used as a potential regulator of tumor growth and metastasis. TSP expression is highly regulated by different hormones and cytokines and is developmentally controlled. TSP stimulates the growth of vascular smooth muscle cells and human foreskin fibroblasts. A combination of IFN-gamma and TNF-alpha inhibits TSP production in these cells.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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别名 |
Thrombospondin-1
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说明书 |
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数量 |
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