全部产品分类
品牌 |
Leading Biology | 货号 |
APR12507G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MC4 Receptor antibody.
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分子量 |
36959 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
MC4 Receptor
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亚型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
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总结 |
MC4R (Melanocortin-4 receptor) belongs to the GPCR superfamily that is responsible for multiple signal transduction pathway which includes the cAMP and MAPK signaling pathways. Expression of MC4R has been reported in brain. From genetic studies of mice and humans, it was established that MC4 receptor plays a critical role in appetite regulation.?Mutation in the MC4R gene is associated with obesity in humans.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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别名 |
melanocortin receptor 4, melanocortin 4 receptor, melanocortin-4 receptor
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说明书 |
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数量 |
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