全部产品分类
品牌 |
Leading Biology | 货号 |
APR08264G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LPL antibody (Center).
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分子量 |
53162 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity).
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
300-327 aa
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靶点 |
This LPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human LPL.
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亚型 |
Rabbit Ig
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通用名 |
LIPD
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基因ID |
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UniProt ID |
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功能 |
The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity).
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总结 |
LPL encodes lipoprotein lipase, which is expressed inheart, muscle, and adipose tissue. LPL functions as a homodimer,and has the dual functions of triglyceride hydrolase andligand/bridging factor for receptor-mediated lipoprotein uptake.Severe mutations that cause LPL deficiency result in type Ihyperlipoproteinemia, while less extreme mutations in LPL arelinked to many disorders of lipoprotein metabolism. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
FC, WB, IHC-P, E
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稀释方法 |
FC~~1:25
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Lipoprotein lipase, LPL, LPL, LIPD
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图像 |
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说明书 |
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数量 |
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