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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > ACE Antibody (C-term)

ACE Antibody (C-term)

货号 货期 规格 / 价格 询价
APG01477G 100 μl / ¥4950

ACE Antibody (C-term)

品牌

Leading Biology

货号

APG01477G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACE antibody (C-term).

分子量

149715 Da

细胞定位

Antigen Cellular Localization: Angiotensin-converting enzyme, soluble form: Secreted

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

1274-1306 aa

靶点

This ACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from the C-terminal region of human ACE.

亚型

Rabbit Ig

通用名

DCP, DCP1

基因ID

UniProt ID

功能

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

总结

ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1

图像

Western blot analysis of anti-ACE Antibody (C-term) (Cat. APG01477G) in mouse lung tissue lysates (35ug/lane). ACE (arrow) was detected using the purified Pab.

说明书

数量

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