品牌 |
Leading Biology | 货号 |
APG02905G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYP2W1 antibody (N-term).
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分子量 |
53844 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum lumen. Cell membrane. Note=About 8% are expressed on the cell surface.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
7-33 aa
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靶点 |
This CYP2W1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human CYP2W1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Actives also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743).
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总结 |
CYP2W1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Cytochrome P450 2W1, 11414-, CYPIIW1, CYP2W1
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图像 |
Western blot analysis of lysates from MCF-7, HepG2 cell line (from left to right), using CYP2W1 Antibody (N-term)( APG02905G). APG02905G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP2W1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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