全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08140G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TEF antibody (C-term).
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分子量 |
33248 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
213-240 aa
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靶点 |
This TEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human TEF.
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亚型 |
Rabbit Ig
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通用名 |
KIAA1655
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that binds to and transactivates the TSHB promoter. Binds to a minimal DNA-binding sequence 5'- [TC][AG][AG]TTA[TC][AG]-3'.
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总结 |
Thyrotroph embryonic factor (TEF), a transcription factor,is a member of the PAR (proline and acidic amino acid-rich)subfamily of basic region/leucine zipper (bZIP) transcriptionfactors. It is expressed in a broad range of cells and tissues inadult animals, however, during embryonic development, TEFexpression appears to be restricted to the developing anteriorpituitary gland, coincident with the appearance ofthyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to,and transactivate the TSHB promoter. It shows homology (in thefunctional domains) with other members of the PAR-bZIP subfamily oftranscription factors, which include albumin D box-binding protein(DBP), human hepatic leukemia factor (HLF) and chicken vitellogeningene-binding protein (VBP); VBP is considered the chicken homologueof TEF. Different members of the subfamily can readily formheterodimers, and share DNA-binding, and transcriptional regulatoryproperties. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Thyrotroph embryonic factor, TEF, KIAA1655
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图像 |
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说明书 |
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数量 |
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