全部产品分类
品牌 |
Leading Biology | 货号 |
AMM05807G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRYGD antibody (Center).
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分子量 |
20738 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
73-101 aa
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靶点 |
This CRYGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human CRYGD.
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亚型 |
Rabbit Ig
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通用名 |
CRYG4
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基因ID |
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UniProt ID |
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功能 |
Crystallins are the dominant structural components of the vertebrate eye lens.
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总结 |
Crystallins are separated into two classes:taxon-specific, or enzyme, and ubiquitous. The latter classconstitutes the major proteins of vertebrate eye lens and maintainsthe transparency and refractive index of the lens. Since lenscentral fiber cells lose their nuclei during development, thesecrystallins are made and then retained throughout life, making themextremely stable proteins. Mammalian lens crystallins are dividedinto alpha, beta, and gamma families; beta and gamma crystallinsare also considered as a superfamily. Alpha and beta families arefurther divided into acidic and basic groups. Seven protein regionsexist in crystallins: four homologous motifs, a connecting peptide,and N- and C-terminal extensions. Gamma-crystallins are ahomogeneous group of highly symmetrical, monomeric proteinstypically lacking connecting peptides and terminal extensions. Theyare differentially regulated after early development. Fourgamma-crystallin genes (gamma-A through gamma-D) and threepseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in agenomic segment as a gene cluster. Whether due to aging ormutations in specific genes, gamma-crystallins have been involvedin cataract formation.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 4, CRYGD, CRYG4
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图像 |
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说明书 |
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数量 |
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