全部产品分类
品牌 |
Leading Biology | 货号 |
APR12252G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GPRC6A antibody (Center).
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分子量 |
104753 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
489-517 aa
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靶点 |
This GPRC6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-517 amino acids from the Central region of human GPRC6A.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
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总结 |
Members of family C of the G protein-coupled receptor(GPCR) superfamily, such as GPRC6A, are characterized by anevolutionarily conserved amino acid-sensing motif linked to anintramembranous 7-transmembrane loop region. Several members ofGPCR family C, including GPRC6A, also have a long N-terminal domain(summary by Pi et al., 2005 [PubMed 16199532]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
G-protein coupled receptor family C group 6 member A, hGPRC6A, G-protein coupled receptor GPCR33, hGPCR33, GPRC6A
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图像 |
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说明书 |
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数量 |
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