品牌 |
Leading Biology | 货号 |
AMM05725G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD97 antibody (C-term).
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分子量 |
91869 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
707-736 aa
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靶点 |
This CD97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 707-736 amino acids from the C-terminal region of human CD97.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
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总结 |
This gene is a member of the EGF-TM7 family of class IIseven-span transmembrane (7-TM) molecules, likely encoded by a genecluster on the short arm of chromosome 19. The encoded product is aglycoprotein that is present on the surface of most activatedleukocytes and spans the membrane seven times, which is a definingfeature of G protein-coupled receptors. The protein has an extendedextracellular region with several N-terminal epidermal growthfactor (EGF)-like domains, which mediate binding to its cellularligand, decay accelerating factor (DAF, CD55), a regulatory proteinof the complement cascade. The presence of structural featurescharacteristic of extracellular matrix proteins and transmembraneproteins suggests that this protein is a receptor involved in bothcell adhesion and signaling processes early after leukocyteactivation. Alternative splicing has been observed for this geneand three variants have been found.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97
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图像 |
CD97 Antibody (C-term) (Cat. AMM05725G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CD97 antibody detected the CD97 protein (arrow).
CD97 Antibody (C-term) (Cat. AMM05725G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD97 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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