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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > DOK7 Antibody (N-term)

DOK7 Antibody (N-term)

货号 货期 规格 / 价格 询价
AMM06947G 100 μl / ¥4950

DOK7 Antibody (N-term)

品牌

Leading Biology

货号

AMM06947G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOK7 antibody (N-term).

分子量

53097 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Peripheral membrane protein. Cell junction, synapse. Note=Accumulates at neuromuscular junctions

宿主

Rabbit

种属反应性

Mouse

免疫原

26-55 aa

靶点

This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.

亚型

Rabbit Ig

通用名

C4orf25

基因ID

UniProt ID

功能

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

总结

The protein encoded by this gene is essential forneuromuscular synaptogenesis. The protein functions in aneuralactivation of muscle-specific receptor kinase, which is requiredfor postsynaptic differentiation, and in the subsequent clusteringof the acetylcholine receptor in myotubes. This protein can alsoinduce autophosphorylation of muscle-specific receptor kinase.Mutations in this gene are a cause of familial limb-girdlemyasthenia autosomal recessive, which is also known as congenitalmyasthenic syndrome type 1B. Alternative splicing results inmultiple transcript variants.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25

图像

DOK7 Antibody (N-term) (Cat. AMM06947G) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the DOK7 antibody detected the DOK7 protein (arrow).

说明书

数量

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