全部产品分类
品牌 |
Leading Biology | 货号 |
APR10490G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TMEM49 antibody (C-term).
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分子量 |
46238 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cell membrane; Multi- pass membrane protein. Vacuole membrane; Multi-pass membrane protein Endoplasmic reticulum
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
377-406 aa
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靶点 |
This TMEM49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the C-terminal region of human TMEM49.
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亚型 |
Rabbit Ig
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通用名 |
TDC1, TMEM49
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基因ID |
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UniProt ID |
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功能 |
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
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总结 |
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis (By similarity).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Vacuole membrane protein 1, Transmembrane protein 49, VMP1, TDC1, TMEM49
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图像 |
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说明书 |
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数量 |
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