全部产品分类
品牌 |
Leading Biology | 货号 |
APR07986G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL6 antibody (Center).
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分子量 |
23718 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
27-55 aa
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靶点 |
This IL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the Central region of human IL6.
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亚型 |
Rabbit Ig
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通用名 |
IFNB2
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基因ID |
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UniProt ID |
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功能 |
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
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总结 |
This gene encodes a cytokine that functions ininflammation and the maturation of B cells. The protein isprimarily produced at sites of acute and chronic inflammation,where it is secreted into the serum and induces a transcriptionalinflammatory response through interleukin 6 receptor, alpha. Thefunctioning of this gene is implicated in a wide variety ofinflammation-associated disease states, including suspectibility todiabetes mellitus and systemic juvenile rheumatoid arthritis.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, IHC-P, E
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稀释方法 |
WB~~1:1000
FC~~1:10~50
IHC-P~~1:10~50
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别名 |
Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
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图像 |
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说明书 |
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数量 |
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