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S100A1 Antibody (C-term)

APR13180G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR13180G		100 μl / ￥4950

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S100A1 Antibody (C-term)

品牌	Leading Biology	货号	APR13180G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S100A1 antibody (C-term).
分子量	10546 Da
细胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
种属反应性	Human
免疫原	45-75 aa
靶点	This S100A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-75 amino acids from the C-terminal region of human S100A1.
亚型	Rabbit Ig
通用名	S100A
基因ID	6271
UniProt ID	P23297
功能	Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
总结	The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may functionin stimulation of Ca2+-induced Ca2+ release, inhibition ofmicrotubule assembly, and inhibition of protein kinase C-mediatedphosphorylation. Reduced expression of this protein has beenimplicated in cardiomyopathies.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, E
稀释方法	WB~~1:1000 IHC-P~~1:50~100
别名	Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100A1, S100A
图像	S100A1 Antibody (C-term) (Cat. APR13180G) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the S100A1 antibody detected the S100A1 protein (arrow). S100A1 Antibody (C-term) (Cat. APR13180G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of S100A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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