全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08615G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DHH antibody (Center).
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分子量 |
43577 Da
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细胞定位 |
Antigen Cellular Localization:
Desert hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
195-223 aa
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靶点 |
This DHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human DHH.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
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总结 |
This gene encodes a member of the hedgehog family. Thehedgehog gene family encodes signaling molecules that play animportant role in regulating morphogenesis. This protein ispredicted to be made as a precursor that is autocatalyticallycleaved; the N-terminal portion is soluble and contains thesignalling activity while the C-terminal portion is involved inprecursor processing. More importantly, the C-terminal productcovalently attaches a cholesterol moiety to the N-terminal product,restricting the N-terminal product to the cell surface andpreventing it from freely diffusing throughout the organism.Defects in this protein have been associated with partial gonadaldysgenesis (PGD) accompanied by minifascicular polyneuropathy. Thisprotein may be involved in both male gonadal differentiation andperineurial development.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Desert hedgehog protein, DHH, HHG-3, Desert hedgehog protein N-product, Desert hedgehog protein C-product, DHH
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图像 |
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说明书 |
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数量 |
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