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> 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-Ser535,539 Interferon-α Receptor, Type I, Subunit I Antibody品牌 |
Leading Biology | 货号 |
APR03385G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser535,539 Interferon-α Receptor, Type I, Subunit I Antibody.
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分子量 |
110-130 KDa
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宿主 |
Rabbit
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种属反应性 |
Rat
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靶点 |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser535/539 conjugated to KLH.
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基因ID |
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UniProt ID |
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总结 |
Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-α Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~ 1:1000
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图像 |
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说明书 |
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数量 |
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