全部产品分类
品牌 |
Leading Biology | 货号 |
APR00012G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DFF45 Antibody.
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分子量 |
36572 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Mouse, Rat
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靶点 |
DFF45
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亚型 |
Rabbit IgG
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通用名 |
Icad
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基因ID |
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UniProt ID |
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功能 |
Inhibitor of the caspase-activated DNase (DFF40).
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总结 |
Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as many other types of diseases. Recently, a human DNA fragmentation factor (DFF45) was identified. DFF is composed of two subunts: DFF40 and DFF45. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40’s activation as a nuclease. Activation of DFF40 can lead to DNA fragmentation, a hallmark of apoptosis.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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说明书 |
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数量 |
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