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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > LZTS1 Antibody (N-term)

LZTS1 Antibody (N-term)

货号 货期 规格 / 价格 询价
APR03772G 100 μl / ¥4950

LZTS1 Antibody (N-term)

品牌

Leading Biology

货号

APR03772G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LZTS1 Antibody (N-term).

分子量

66613 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Cell membrane. Cell projection, dendritic spine Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse Note=Associated with the plasma membrane and with microtubules Detected in dendritic spines, especially in the postsynaptic density (By similarity).

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

77-105 aa

靶点

This LZTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1.

亚型

Rabbit Ig

通用名

FEZ1

基因ID

UniProt ID

功能

Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor.

总结

This gene encodes a tumor suppressor protein that isubiquitously expressed in normal tissues. In uveal melanomas,expression of this protein is silenced in rapidly metastasizing andmetastatic tumor cells but has normal expression in slowlymetastasizing or nonmetastasizing tumor cells. This protein mayhave a role in cell-cycle control by interacting with theCdk1/cyclinB1 complex. This gene is located on chromosomal region8p22. Loss of heterozygosity (LOH) in the 8p arm is a commoncharacteristic of many types of cancer.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

图像

LZTS1 Antibody (N-term) (Cat. APR03772G) western blot analysis in A2058 cell line and mouse brain tissue lysates (35ug/lane).This demonstrates the LZTS1 antibody detected the LZTS1 protein (arrow).

说明书

数量

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