品牌 |
Leading Biology | 货号 |
APR05370G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality p130 Cas Antibody (Ab-410) .
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分子量 |
93 KDa
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细胞定位 |
Antigen Cellular Localization:
Cell junction, focal adhesion. Cytoplasm. Note=Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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免疫原 |
400-430 aa
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通用名 |
CAS, CASS1, CRKAS
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基因ID |
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UniProt ID |
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功能 |
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
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总结 |
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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稀释方法 |
WB~~ 1:1000
IHC~~1:50-1:100
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图像 |
Western blot analysis of lysates from Hela,HepG2 cell line (from left to right),using p130 Cas Antibody (Ab-410) (B0077). B0077 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p130 Cas (Ab-410) antibody . |
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说明书 |
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数量 |
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