全部产品分类
品牌 |
Leading Biology | 货号 |
APR03756G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FCAR Antibody (Center).
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分子量 |
32265 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform A.1: Cell membrane; Single-pass type I membrane protein Isoform A.3: Cell membrane; Single-pass type I membrane protein Isoform B-delta-S2: Secreted.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
58-84 aa
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靶点 |
This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR.
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亚型 |
Rabbit Ig
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通用名 |
CD89
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基因ID |
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UniProt ID |
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功能 |
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
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总结 |
This gene is a member of the immunoglobulin genesuperfamily and encodes a receptor for the Fc region of IgA. Thereceptor is a transmembrane glycoprotein present on the surface ofmyeloid lineage cells such as neutrophils, monocytes, macrophages,and eosinophils, where it mediates immunologic responses topathogens. It interacts with IgA-opsonized targets and triggersseveral immunologic defense processes, including phagocytosis,antibody-dependent cell-mediated cytotoxicity, and stimulation ofthe release of inflammatory mediators. Multiple alternativelyspliced transcript variants encoding different isoforms have beendescribed for this gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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