全部产品分类
品牌 |
Leading Biology | 货号 |
APR11391G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ALSFTD antibody.
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分子量 |
Predicted: 53 kDa Observed: 52 kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Endosome. Lysosome. Cytoplasmic vesicle, autophagosome. Secreted. Note=Detected in the cytoplasm of neurons from post mortem brain tissue (PubMed:21944778). Detected in the nucleus in fibroblasts (PubMed:21944779).
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
ALSFTD; ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
May play a role in endosomal trafficking and autophagy.
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总结 |
ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, ICC, E
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图像 |
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说明书 |
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数量 |
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