全部产品分类
品牌 |
Leading Biology | 货号 |
APR10008G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLC1A7 antibody.
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分子量 |
Predicted: 17, 52, 62, 68 kDa Observed: 52 kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
SLC1A7; SLC1A7 antibody is human and mouse reactive. Multiple isoforms of SLC1A7 are known to exist.
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亚型 |
IgG
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通用名 |
EAAT5
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基因ID |
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UniProt ID |
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功能 |
Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
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总结 |
The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
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说明书 |
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数量 |
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