全部产品分类
品牌 |
Leading Biology | 货号 |
APR12016G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GDPD5 antibody.
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分子量 |
Predicted: 40, 67 kDa Observed: 52 kDa
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细胞定位 |
Antigen Cellular Localization:
Endomembrane system; Multi- pass membrane protein. Cytoplasm, perinuclear region. Cell projection, growth cone. Note=In a punctate perinuclear pattern.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
GDPD5; GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.
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亚型 |
IgG
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通用名 |
GDE2
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基因ID |
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UniProt ID |
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功能 |
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
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总结 |
The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth (2,3). Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer (4).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
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说明书 |
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数量 |
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