品牌 |
Leading Biology | 货号 |
APR08406G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ME1 antibody.
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分子量 |
Predicted: 63 kDa Observed: 63 kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
ME1; ME1 antibody is human, mouse and rat reactive. ME1 antibody is predicted not to cross-react with ME2.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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总结 |
ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1). ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2). It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3). The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4). ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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图像 |
Western blot analysis of ME1 in 293 cell lysate with ME1 antibody at 1 μg/ml.
Immunohistochemistry of ME1 in mouse liver tissue with ME1 antibody at 5 μg/mL. |
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说明书 |
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数量 |
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