品牌 |
Leading Biology | 货号 |
AMM08432G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ULK4 antibody.
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分子量 |
Predicted: 140 kDa Observed: 165 kDa
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
ULK4; ULK4 antibody is human and mouse reactive. Multiple isoforms of ULK4 are known to exist.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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总结 |
ULK4 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1). Knockout of ULK genes results in a severe defect in the autophagy pathway (2). ULK4, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK3, is highly conserved among eukaryotes (3). ULK4 has been implicated as a gene involved in the development of hydrocephalus (3). This neurologic disorder is being used in animal models to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans (4).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
Western blot analysis of ULK4 in 3T3 cell lysate with ULK4 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of ULK4 in human brain tissue with ULK4 antibody at 5 μg/mL.
Immunofluorescence of ULK4 in human brain tissue with ULK4 antibody at 20 μg/mL. |
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说明书 |
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数量 |
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