全部产品分类
品牌 |
Leading Biology | 货号 |
APR11448G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality APPBP2 antibody.
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分子量 |
Predicted: 64 kDa Observed: 57 kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Associated with membranes and microtubules
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
APPBP2; APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist; this antibody will detect both isoforms.
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亚型 |
IgG
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通用名 |
KIAA0228, PAT1
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基因ID |
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UniProt ID |
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功能 |
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
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总结 |
The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
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说明书 |
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数量 |
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