品牌 |
Leading Biology | 货号 |
APR07525G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DDC antibody .
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分子量 |
Predicted: 53 kDa Observed: 50 kDa
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
DDC; DDC antibody is human, mouse and rat reactive.
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亚型 |
IgG
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通用名 |
AADC
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
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总结 |
DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
Western blot analysis of DDC in human lung tissue lysate with DDC antibody at 1 μg/ml.
Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.
Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL. |
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说明书 |
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数量 |
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