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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > DDC Antibody

DDC Antibody

货号 货期 规格 / 价格 询价
APR07525G 0.1 mg / ¥6950

DDC Antibody

品牌

Leading Biology

货号

APR07525G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DDC antibody .

分子量

Predicted: 53 kDa Observed: 50 kDa

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

DDC; DDC antibody is human, mouse and rat reactive.

亚型

IgG

通用名

AADC

基因ID

UniProt ID

功能

Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.

总结

DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

图像

Western blot analysis of DDC in human lung tissue lysate with DDC antibody at 1 μg/ml.

Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.

Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.

说明书

数量

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