全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07735G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SDPR antibody.
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分子量 |
47 kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Membrane, caveola. Note=Colocalizes with CAV1 to caveolae
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
SDPR; It is predicted to not cross-react with other members of the cavin family.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
May play a role in targeting PRKCA to caveolae.
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总结 |
SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
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说明书 |
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数量 |
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