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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > CRIM1 Antibody

CRIM1 Antibody

货号 货期 规格 / 价格 询价
AMM05794G 0.1 mg / ¥6950

CRIM1 Antibody

品牌

Leading Biology

货号

AMM05794G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRIM1 antibody.

分子量

113738 Da

细胞定位

Antigen Cellular Localization: Processed cysteine-rich motor neuron 1 protein: Secreted

宿主

Rabbit

种属反应性

Human

靶点

CRIM1; CRIM1 antibody is human reactive. CRIM1 antibody is predicted to not cross-react with CRIM2.

亚型

IgG

通用名

S52

基因ID

UniProt ID

功能

May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.

总结

CRIM1 Antibody: CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IF, E

图像

Western blot analysis of CRIM1 in Jurkat cell lysate with Crim1 antibody at 1 μg/mL.

Immunofluorescence of CRIM1 in Jurkat cells with CRIM1 antibody at 20 μg/mL.

说明书

数量

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