品牌 |
Leading Biology | 货号 |
APR16106G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GBP6 antibody.
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分子量 |
72427 Da
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
GBP6; GBP6 antibody is predicted to not cross-react with other GBP family members.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Binds GTP, GDP and GMP.
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总结 |
GBP6 Antibody: The guanylate-binding proteins (GBPs), a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN) (1,3). GBP6 is induced by IFN and hydrolyzes GTP to both GDP and GMP. The precise function of GBP6 is still under investigation.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, ICC, E
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图像 |
Western blot analysis of GBP6 in Hela cell lysate with GBP6 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of GBP6 in HeLa cells with GBP6 antibody at 2.5 μg/mL.
Immunofluorescence of GBP6 in HeLa cells with GBP6 antibody at 5 μg/mL. |
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说明书 |
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数量 |
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