品牌 |
Leading Biology | 货号 |
AMM06138G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCNK13 antibody.
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分子量 |
45391 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
KCNK13; KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Potassium channel displaying weak inward rectification in symmetrical K(+) solution.
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总结 |
KCNK13 Antibody: The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
Western blot analysis of KCNK13 in rat brain tissue lysate with KCNK13 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of KCNK13 in human brain tissue with KCNK13 antibody at 5 μg/mL.
Immunofluorescence of KCNK13 in human brain tissue with KCNK13 antibody at 20 μg/mL. |
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说明书 |
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数量 |
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