全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08556G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZIMP7 antibody.
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分子量 |
96537 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Detected at replication foci throughout S phase
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
ZMIZ2; At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
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亚型 |
IgG
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通用名 |
KIAA1886, ZIMP7
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基因ID |
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UniProt ID |
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功能 |
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.
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总结 |
ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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图像 |
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说明书 |
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数量 |
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