品牌 |
Leading Biology | 货号 |
AMM08071G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SYNPO2L antibody.
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分子量 |
102481 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
SYNPO2L;
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Actin-associated protein that may play a role in modulating actin-based shape.
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总结 |
SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 5 μg/mL.
Immunofluorescence of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 20 μg/mL. |
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说明书 |
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数量 |
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