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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > MATN1 Antibody

MATN1 Antibody

货号 货期 规格 / 价格 询价
APC00073G 0.1 mg / ¥6950

MATN1 Antibody

品牌

Leading Biology

货号

APC00073G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MATN1 antibody.

分子量

53701 Da

细胞定位

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

MATN1;

亚型

IgG

通用名

CMP, CRTM

基因ID

UniProt ID

功能

Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.

总结

MATN1 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

图像

Western blot analysis of MATN1 in rat liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of MATN1 in human liver tissue with MATN1 antibody at 5 μg/mL.

Immunofluorescence of MATN1 in Human Liver cells with MATN1 antibody at 20 μg/mL.

说明书

数量

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