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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > TOM70 Antibody

TOM70 Antibody

货号 货期 规格 / 价格 询价
APR10505G 0.1 mg / ¥6950

TOM70 Antibody

品牌

Leading Biology

货号

APR10505G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TOM70 antibody.

分子量

Predicted: 67 kDa Observed: 67 kDa

细胞定位

Antigen Cellular Localization: Mitochondrion outer membrane; Single-pass membrane protein

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

TOMM70A; At least two isoforms of TOM70 are known to exist; this antibody will only detect the larger isoform.

亚型

IgG

通用名

KIAA0719, TOM70

基因ID

UniProt ID

功能

Receptor that accelerates the import of all mitochondrial precursor proteins.

总结

TOM70 Antibody: The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. TOM70, an important member of the TOM complex, contains a tetratricopeptide repeat domain similar to those found in cytosolic chaperones such as Hsp90 and Hsc70 and provides a docking site for these proteins. This interaction is thought to be a critical first step in the TOM70-dependent mitochondrial import, followed by contact between the preprotein and TOM70. After targeting to TOM70, preproteins are translocated through the outer membrane via the TOM40 import pore complex. The precise mechanism of how preproteins progress from TOM70 to TOM40 to full translocation is still unclear.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

图像

Western blot analysis of TOM70 in mouse brain tissue lysate with TOM70 antibody at (A) 0.5 and (B) 1 μg/mL.

Immunohistochemistry of TOM70 in mouse brain tissue with TOM70 antibody at 2.5 μg/mL.

Immunofluorescence of TOM70 in Mouse Brain tissue with TOM70 antibody at 5 μg/mL.

说明书

数量

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