全部产品分类
品牌 |
Leading Biology | 货号 |
AMM06191G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIF5 antibody.
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分子量 |
Predicted: 105, 114 kDa Observed: 118 kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
KIF5A; KIF5 has at least three known isoforms; this antibody recognizes all three.
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亚型 |
IgG
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通用名 |
NKHC1
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基因ID |
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UniProt ID |
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功能 |
Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL).
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总结 |
KIF5 Antibody: The kinesin superfamily proteins (KIFs) are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. Mutations in one of the three isoforms of KIF5 (KIF5A) are thought to be involved in hereditary spastic paraplegias.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, ICC, E
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图像 |
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说明书 |
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数量 |
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