全部产品分类
品牌 |
Leading Biology | 货号 |
APG02226G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Bcl-B antibody.
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分子量 |
21973 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion. Nucleus membrane
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
BCL2L10;
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亚型 |
IgG
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通用名 |
BCLB
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基因ID |
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UniProt ID |
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功能 |
Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.
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总结 |
Bcl-B Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, ICC, E
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别名 |
Bcl-B Antibody: Boo, Diva, BCL-B, BCLB, Bcl-2-like protein 10, Anti-apoptotic protein NrH, Bcl2-L-10, BCL2-like 10 (apoptosis facilitator)
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图像 |
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说明书 |
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数量 |
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