全部产品分类
品牌 |
Leading Biology | 货号 |
APR13072G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality rat TRPV1 (extracellular) antibody.
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分子量 |
94948 Da
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宿主 |
Rabbit
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种属反应性 |
Rat
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靶点 |
Peptide (C)NSLPMESTPHK*SRGS,??corresponding to amino acid residues 605-619 of rat TRPV1 with replacement of cysteine 616 (C616) with serine (*S) (Accession O35433). 3rd extracellular loop.Recognizes TRPV1 from rat samples only.
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基因ID |
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UniProt ID |
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总结 |
TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family; the TRPA, TRPML, and TRPP).1-4 The TRPV subfamily consists of six members, TRPV1-6.5TRPV1 channel has many activators among them heat, protons, vanilloids like capsaicin, reiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation.6,7TRPV1 is expressed predominantly in nociceptors and in sensory neurons.Recent studies demonstrated involvement of TRPV1 in apoptosis where inhibition of the receptor prevented apoptosis.8,9Abgent is pleased to offer a highly specific antibody directed against an extracellular epitope of the rat TRPV1 channel. Anti-Rat TRPV1 (extracellular) antibody (#AG1453) can be used for western blot and immunohistochemistry applications. It has been designed to recognize only rat TRPV1 samples.
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形式 |
Affinity purified antibody, Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, LCI
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稀释方法 |
WB~~1:200-1:2000
IHC~~1:100
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别名 |
Transient receptor potential cation channel subfamily V member 1, TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like, Trpv1, Vr1, Vr1l
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图像 |
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说明书 |
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数量 |
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