全部产品分类
品牌 |
Leading Biology | 货号 |
AMM06230G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KV7.1 (KCNQ1) antibody.
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分子量 |
74699 Da
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Peptide (C)TYEQLTVPRRGPDEGS, corresponding to amino acid residues 661-676 of human Kv7.1 (Accession number P51787). Intracellular, C-terminus.
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基因ID |
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UniProt ID |
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总结 |
KV7.1 (KCNQ1) is part of a voltage-gated K+ family that includes 5 other members (KCNQ1-5). The channel has been intensively studied since it was found that together with MinK (Isk) itunderlay the cardiac Iks current that controls the duration of the action potential of the human heart. Indeed mutations on either KV7.1 or MinK can be responsible for long QT syndrome, a cardiac disorderthat causes arrhythmias and sudden death.Although KV7.1 expression and function has been mainly investigated in relation with cardiac functionthe channel is widely distributed in epithelial tissues. There it has been implicated in physiologicalfunctions such as: regulation of acid secretion in the stomach and Cl- secretion into the colon.
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形式 |
Affinity purified antibody, Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IP
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稀释方法 |
WB~~1:200-1:2000
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别名 |
Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv71, KCNQ1, KCNA8, KCNA9, KVLQT1
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图像 |
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说明书 |
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数量 |
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