全部产品分类
品牌 |
Leading Biology | 货号 |
APR12677G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2Y12 Receptor antibody.
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分子量 |
39439 Da
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Peptide (C)KTTRPFKTSNPKNLLGAK,?? corresponding to amino acid residues 125-142 of human P2Y12 receptor. (Accession Q9H244). Intracellular, 2nd Cytoplasmic loop.
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基因ID |
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UniProt ID |
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总结 |
The P2Y receptors belong to the G-protein coupled receptors superfamily.They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP AND UDPA. Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.1-3The P2Y12 receptor is co-expressed with P2Y1 receptor on platelets leading to shapechange, aggregation, and rise in intracellular Ca2+upon activation.The only other expression of P2Y12 was found in brain, according to results of reversetranscription-polymerase chain reaction and northern blotting.4The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders.4
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形式 |
Affinity purified antibody, Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~1:200-1:2000
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别名 |
P2Y purinoceptor 12, P2Y12, ADP-glucose receptor, ADPG-R, P2T(AC), P2Y(AC), P2Y(cyc), P2Y12 platelet ADP receptor, P2Y(ADP), SP1999, P2RY12, HORK3
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图像 |
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说明书 |
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数量 |
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