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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

货号 货期 规格 / 价格 询价
AMM06021G 100 μg / ¥5450

Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

品牌

Leading Biology

货号

AMM06021G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) antibody.

分子量

127179 Da

细胞定位

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

宿主

Chicken

种属反应性

Human, Mouse, Rat

通用名

CD11B, CR3A

基因ID

UniProt ID

功能

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

形式

Phosphate-buffered (10 mM) isotonic saline (0.9%, w.v) with sodium azide (0.02%, w/v) added as a preservative.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IHC, ICC

别名

Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, ITGAM, CD11B, CR3A

图像

Mac-1 staining of the microglial cells in mouse cerebral cortex (red). Photo courtesy of Dr. Felix Eckenstein, University of Vermont.

说明书

数量

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