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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > PANX1 Antibody (NT)

PANX1 Antibody (NT)

货号 货期 规格 / 价格 询价
APR12717G 100 μg / ¥5450

PANX1 Antibody (NT)

品牌

Leading Biology

货号

APR12717G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PANX1 antibody (NT).

分子量

48050 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00351}

宿主

Rabbit

种属反应性

Human, Mouse

靶点

PANX1

亚型

Rabbit IgG1

通用名

MRS1

基因ID

UniProt ID

功能

Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.

总结

The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

别名

Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028

图像

Western blot analysis of PANX1 in human ovary tissue lysate with PANX1 antibody at 1μg/mL.

说明书

数量

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