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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > HFE2 / Hemojuvelin Antibody (clone 1C12)

HFE2 / Hemojuvelin Antibody (clone 1C12)

货号 货期 规格 / 价格 询价
AMM05340G 50 μg / ¥5450

HFE2 / Hemojuvelin Antibody (clone 1C12)

品牌

Leading Biology

货号

AMM05340G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HFE2 / Hemojuvelin antibody (clone 1C12).

分子量

45kDa

细胞定位

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor

宿主

Mouse

种属反应性

Human

靶点

Human HFE2

克隆号

1C12

通用名

HJV, RGMC

基因ID

UniProt ID

功能

Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin.

总结

Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

IHC-P (5 μg/ml)

别名

Hemojuvelin, Hemochromatosis type 2 protein, RGM domain family member C, HFE2, HJV, RGMC

图像

Anti-HFE2 antibody IHC of human small intestine.

说明书

数量

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