品牌 |
Leading Biology | 货号 |
APR13929G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality USP9X antibody - C-terminal region.
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分子量 |
292kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell projection, growth cone.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
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通用名 |
DFFRX, FAM, USP9
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基因ID |
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UniProt ID |
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功能 |
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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别名 |
Probable ubiquitin carboxyl-terminal hydrolase FAF-X, 3.4.19.12, Deubiquitinating enzyme FAF-X, Fat facets in mammals, hFAM, Fat facets protein-related, X-linked, Ubiquitin thioesterase FAF-X, Ubiquitin-specific protease 9, X chromosome, Ubiquitin-specific-processing protease FAF-X, USP9X, DFFRX, FAM, USP9
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图像 |
mouse 3T3 s
Sample Type: 1. total HeLa cell extract (100ug)2. total HeLa cell extract incubated with HA-UbVME (100ug)3. Rat Liver cytosolic extract (100ug)4. Rat Liver cytosolic extract incubated with HA-UbVME (100ug)Primary Dilution: 1:1000 Secondary Antibody: alkaline phosphatase-conjugated anti-rabbitSecondary Dilution: 1:1000Image Submitted by: Andreia CarvalhoIBMC-OBF, Portugal |
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说明书 |
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数量 |
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