全部产品分类
品牌 |
Leading Biology | 货号 |
APR09223G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser295 Beclin-1 antibody.
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分子量 |
60 KDa
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser295 conjugated to KLH.
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基因ID |
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UniProt ID |
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总结 |
Beclin-1 plays a key role in tumor suppression and autophagy. It has been suggested that autophagy proteins such as beclin-1 can inhibit tumorigenesis and that decreased expression of these proteins may contribute to the development of human malignancies (Liang et al., 1999). Akt-mediated phosphorylation of beclin-1 at Ser295 has been shown to decrease autophagy and promote oncogenesis (Wang et al., 2012).
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形式 |
Prepared from rabbit serum by affinity purification via sequentialchromatography on phospho- and dephosphopeptide affinity columns.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~ 1:250
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别名 |
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197
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图像 |
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说明书 |
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数量 |
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