全部产品分类
品牌 |
Leading Biology | 货号 |
APR12823G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser603 Synapsin I antibody.
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分子量 |
78 KDa
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宿主 |
Rabbit
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种属反应性 |
Rat
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靶点 |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 conjugated to KLH.
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基因ID |
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UniProt ID |
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总结 |
Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayak etal., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability ofsynaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis isregulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002). Serine 603 is the site onsynapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases(Sakurada et al., 2002; Czernik et al., 1987). Phosphorylation of this site is thought to regulatesynaptic vesicle function (Nayak et al., 1996; Bahler and Greengard, 1987; McGuinness et al.,1989).
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形式 |
Prepared from rabbit serum by affinity purification via sequentialchromatography on phospho- and dephosphopeptide affinity columns.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~ 1:1000
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别名 |
Synapsin-1, Synapsin I, SYN1
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图像 |
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说明书 |
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数量 |
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