全部产品分类
品牌 |
Leading Biology | 货号 |
APR12835G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ser774 Dynamin antibody.
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分子量 |
95 KDa
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宿主 |
Sheep
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种属反应性 |
Rat
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靶点 |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser774 conjugated to KLH.
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基因ID |
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UniProt ID |
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总结 |
Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001; Graham et al., 2002; Tsuboi et al., 2002). Cyclin dependent protein kinase 5 phosphorylates dynamin at Ser774 and Ser778 that are the phosphorylation sites on dynamin phosphorylated in vivo (Tan et al., 2003). Phosphorylation of Ser774 by GSK3 has recently been shown to control activity-dependent bulk endocytosis of synaptic vesicles (Clayton et al., 2010)
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形式 |
Prepared from sheep serum by affinity purification via sequentialchromatography on phospho- and dephosphopeptide affinity columns.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~ 1:1000
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别名 |
Dynamin-1, B-dynamin, D100, Dynamin, brain, Dnm1, Dnm
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图像 |
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说明书 |
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数量 |
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